The Checkpoints for Cell Division

Which of these checkpoints determines if cell division has occurred properly?

A) M checkpoint
B) G1 checkpoint
C) G2 checkpoint

The checkpoint that determines if cell division has occurred properly is:

A. M Checkpoint

Cell division is a crucial process in the life cycle of cells. To ensure that cell division has occurred properly, cells go through specific checkpoints to assess their readiness and accuracy in dividing. One of these essential checkpoints is the M checkpoint.

The M checkpoint, also known as the mitotic checkpoint, is responsible for determining whether all sister chromatids are correctly attached to the spindle during cell division. If any errors or abnormalities are detected at this checkpoint, the cell cycle may be halted to prevent the formation of daughter cells with genetic defects.

In contrast, the G1 and G2 checkpoints are pre-division checkpoints that monitor different aspects of the cell's readiness to proceed with division. The G1 checkpoint assesses the cell's size, nutrient availability, and DNA integrity, while the G2 checkpoint checks for DNA replication completeness and damage repair before entering the mitotic phase.

Therefore, to ensure successful and accurate cell division, it is crucial for cells to pass through the M checkpoint and meet the requirements set by this critical regulatory mechanism.