Juvenile Polyps: Understanding the Histological Features
What histological findings are characteristic of juvenile polyps?
A) Surface ulceration and cystically dilated crypts filled with neutrophils
B) Glandular atrophy and fibrous tissue proliferation
C) Hyperplastic goblet cells and nuclear hyperchromasia
D) Dysplastic changes and increased mitotic activity
Answer:
Juvenile polyps predominantly occur in the large intestine and rectum of children. These polyps are characterized by surface ulceration and cystically dilated crypts filled with inflammatory cells and mucus.
Juvenile polyps are a type of polyp that primarily occurs in the large intestine and rectum of children. Histologically, they are characterized by surface ulceration and cystically dilated crypts filled with inflammatory cells and mucus. These crypts, known as the crypts of Lieberkühn, are part of the intestinal glands.
These glands produce intestinal juice, a mixture of water and mucus, and are formed by cells that line the crevices between the villi. They secrete mucus that aids in the movement of feces and protects the intestine from the effects of acids and gases produced by enteric bacteria.
They are not typically associated with glandular atrophy, fibrous tissue proliferation, hyperplastic goblet cells, nuclear hyperchromasia, or dysplastic changes and increased mitotic activity.